Weekly Mind Reader: Is It All Black and White?

by Staff Writer
November 22, 2024 at 8:20 AM UTC

This week, we’ve got commentary on the opioids legacy, insight into neuropsychological testing, and sex differences in PTSD.

This week, we expose racial differences in postpartum mood disorders, explore cannabis use and birth defects, and tardive dyskinesia.

Postpartum Mood Disorders Show Racial Disparities

A new study appearing in The Journal of Clinical Psychiatry this week uncovers notable racial disparities in postpartum mood disorders, affecting maternal and child health.

Researchers analyzed incidence rates of major depressive disorder (MDD) and bipolar disorder (BD) among Black and White postpartum women who screened positive for depression at a Pittsburgh hospital. Their results reveal that Black women were nearly twice as likely to screen positive for MDD compared to White women.

The prevalence of MDD was similar between Black and White participants, but, Black women struggled more with BD than their White counterparts. Black participants also:

  • Experienced more severe depressive symptoms.
  • Higher trauma rates.
  • Greater comorbidity with post-traumatic stress disorder (PTSD).

White women, on the other hand, appeared to be more likely to report generalized anxiety disorder and eating disorders.

Researchers noted socioeconomic disparities among the participants, with White women more likely to be married, privately insured, and highly educated. 

Researchers stressed the need for trauma-informed care and culturally tailored interventions, since childhood trauma strongly correlated with mood disorder severity regardless of the racial group.

The study also highlights the importance of structured diagnostic interviews to cut back racial biases in diagnosing postpartum mood disorders. Caregivers typically under-diagnose Black women for MDD and confuse schizophrenia with BD, which leads to treatment gaps.

The researchers concluded by calling for lower depression screening cutoffs for Black women and greater awareness of postpartum BD in racial minorities. They also pushed for better resource allocation to address these disparities, emphasizing that early intervention could mitigate maternal morbidity and mortality.

IN OTHER PSYCHIATRY AND NEUROLOGY NEWS

  • Another JCP report shows that growing cannabis use during pregnancy slightly – but significantly – raises the risk of birth defects.
  • In The Primary Care Companion for CNS Disorders, a report details how early detection and treatment with VMAT-2 inhibitors – and some alternative interventions – can improve the quality of life of tardive dyskinesia patients.
  • In a letter to the editor, a group of readers argue that ongoing support from perinatal social workers is more effective than a one-time psychiatric assessment for maternal-fetal surgery patients.
  • Check out our editorial focus on Emerging Approaches in Schizophrenia.
  • And, finally, read up on the latest PTSD research.

Original Research

Olanzapine/Samidorphan Effects on Weight Gain: An Individual Patient Data Meta-Analysis of Phase 2 and 3 Randomized Double-Blind Studies

Treatment with a combination of olanzapine and samidorphan was associated with less weight gain and reduced risk of reaching ≥7% or ≥10% gain in body weight versus olanzapine over 12 weeks.

Christoph U. Correll and others

Case Report

Image of a doctor holding antipsychotics

Antipsychotic-Induced Tardive Lingual Dystonia Presenting With Bradycardia

The authors present a rare case of antipsychotic-induced lingual dystonia that led to hemodynamic changes in a 15-year-old boy.

Diveesha Munipati and others