This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Article

Limitations of Contemporary Antidepressants: Tolerability

George I. Papakostas, MD

Published: August 15, 2007

Article Abstract

Antidepressant side effects are common and persistent. They can contribute to discomfort, distress,disability, morbidity, and mortality and can compromise the efficacy of treatments. Reducing the sideeffect burden, either by developing treatments that have a lower incidence of side effects or by usingtreatment strategies that alleviate side effects, would improve the standard of care for mood and anxietydisorders. In this article, the rates of common adverse events among the newer (posttricyclic era)antidepressants are compared with those among the selective serotonin reuptake inhibitors, the mostpopular, contemporary first-line treatments for depression.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 68

Quick Links: Depression (MDD)